This week, a couple colleagues and I got an email from a random Internet person about some work we had done and published. It was a credentialed person with a legitimate question and he wanted to see what our take on it was. One of my colleagues responded with something reasonably intelligent, and I wanted to follow up a little bit, so I did a 'reply all' and added my two cents. My colleague hits 'reply all' and then posts "That's a good point, but probably a little over the head of our friend here." Unfortunately "our friend here" was CCed on the message. Whoops. The comment wasn't even that warranted, but I think we lost a fan there. FOCUS: When have you, or someone with whom you are acquainted, done something completely cringeworthy like this? Did you try to apologize or otherwise take your foot out of your mouth? Run for the hills? Get plastic surgery to try to change your appearance so you would never have to face the consequences?